The timing of the raid was notable as Ukrainian Popovych appeared in front of a grand jury in Los Angeles on Nov. 3 as part of an open investigation into doping in cycling.
Police and custom officials raided the house in Tuscany on Thursday and seized computers and mobile phones along with unspecified substances.
Italian newspaper Gazzetta dello Sport reported that the search warrant was issued by public prosecutor Benedetto Roberti, who is leading several doping investigations in Italy.
Popovych has been working as a teammate of Armstrong's since their days at Discovery Channel, also riding alongside the seven-time tour winner on the Astana and RadioShack teams.
In recent weeks, the federal prosecutors have subpoenaed several of Armstrong's former teammates and associates including coach Allen Lim and Oakley representative Stephanie McIlvain.
As usual, no comment from Federal investigators about the investigation which is headed by Food and Drug Administration agent Jeff Novitzky.
Yes, we are tired, tired of this investigation--no, witch hunt-- going after the most tested rider in the world (Armstrong), who has been tested at all times of the day, morning, noon and night, in all regions of the world, by surprise, at a moment's notice. There is no more testing done possibly in any other sport in the world than there is of pro cyclists, thanks to progressive action by the world cycling organization the UCI.
Despite rigorous, if not truly invasive testing of Armstrong (and hundreds of other pro cyclists who have made it), this is not the first time that a witch hunt has organized with such ferocity against Armstrong.
He's been dogged by doubters, naysayers, witch hunters, media hunters, and their ilk since he started winning the Tour de France the first time in the 1990's. What about Miguel Indurain? Eddy Merckx? What about opening investigations of them? It's never too late, you know. In fact, let's raid all the homes of all cyclists, in the world! That would be a real pay off! (Well it could yield some cheaters, but I think our point is made.)
And let's let all the professional ball players be--because you know, they are too busy with their billion dollar mansions, racing cars, illicit girlfriends and ecstasy parties to take performance enhancing drugs.
The 30-year-old Popovych turned professional in 2002 with the Landbouwkrediet-Colnago Team after becoming the first and only amateur to win the silver medal and then the gold medal in the U23 UCI World Road Race Championships in successive years (2000 and 2001), according to the RadioShack team site. Popovych has also raced professionally for Silence-Lotto.